Peripheral Arterial Disease is a common circulatory problem in which narrowed arteries reduce blood flow to your limbs. Arteries supply blood to your legs and arms as well as many vital organs. Symptoms of PAD are weakness, numbness, heaviness and tiredness of legs and cramping in your calf (or calves). PAD is one of the leading causes of need for amputation. Risk factors include smoking, diabetes, high blood pressure, elevated cholesterol and family history. If you have any of these signs or symptoms and risk factors, it is important to inform your physician.