Debra Wood, RN
A peptic ulcer is a sore in the lining of the stomach or the first part of the small intestine. This area of the small intestine is called the duodenum. Peptic ulcers may be named by their location:
Treatment may include antibiotics, medications that heal the ulcer and protect the stomach, and lifestyle changes. Surgery may be needed for ulcers that bleed, obstruct, perforate, or don't heal with other treatments.
Upsets in the balance of stomach acid and digestive juices can lead to an ulcer. This can be caused by:
Less common causes include:
Factors that increase your chances of peptic ulcer include:
Peptic ulcers do not always cause symptoms. Symptoms may come and go. Food or fluids sometimes make symptoms better. Having an empty stomach may make symptoms worse. However, symptoms can occur at any time.
Symptoms may include:
Ulcers can cause serious problems and severe abdominal pain. One problem is bleeding. Bleeding symptoms may include:
A perforated ulcer is a break through the wall of the stomach or duodenum. It causes sudden and severe pain.
The doctor will ask about your symptoms and medical history. A physical exam will be done.
Tests may include:
Talk to your doctor about the best treatment plan for you. Treatment options may include one or more of the following:
Your doctor may recommend:
You and your doctor will discuss lifestyle changes. These may include:
Surgery and/or endoscopy may be recommended for:
This may be done to stop bleeding. A thin, lighted tube is inserted down the throat into the stomach or intestine. Heat, electricity, epinephrine, or a substance called fibrin glue can then be applied to the area. This should stop the blood flow.
Surgery for peptic ulcers is rare, but it can greatly reduce acid production. Common procedures include:
To reduce your chance of getting
To reduce your chance of getting a peptic ulcer from NSAIDs:
The American College of Gastroenterology
American Gastroenterological Association
Canadian Association of Gastroenterology
H. pylori and peptic ulcers. National Digestive Diseases Information Clearinghouse website. Available at: http://digestive.niddk.nih.gov/ddiseases/pubs/hpylori/index.aspx. Updated April 30, 2012. Accessed April 29, 2013.
Meurer LN, Bower DJ. Management of
Am Fam Physician. 2002;65(7):1327-36.
Peptic ulcer disease. American College of Gastroenterology website. Available at: http://patients.gi.org/topics/peptic-ulcer-disease. Accessed April 29, 2013.
Peptic ulcer disease. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what. Updated April 22, 2013. Accessed April 29, 2013.
Understanding peptic ulcer disease.
American Gastroenterological Association website. Available at:
http://www.gastro.org/patient-center/digestive-conditions/peptic-ulcer-disease. Published April 23, 2010. Accessed April 29, 2013.
Last reviewed April 2013 by Daus Mahnke, MD; Brian Randall, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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